Zhao Xinyue obtained her doctoral degree from Xiamen University in 2025 and joined Shantou University in 2026, where she currently serves as a lecturer in the Department of Biomedical Engineering at the College of Engineering.
Research Fields
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Tumor microenvironment-responsive theranostic probes; Novel targeted covalent drugs
Education
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2021.09–2025.06 Xiamen University, College of Chemistry and Chemical Engineering, Ph.D.
2018.12–2021.06 Northwest University, College of Chemistry and Materials Science, M.S.
2014.09–2018.06 Nanjing Normal University, College of Teacher Education, B.S.
Work Experience
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2026.06 - Shantou University, Department of Biomedical Engineering, Lecturer
Current Project
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STU Scientific Research Initiation Grant (SRIG), 2026.07-2029.06
Publications
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1. Xinyue Zhao, Yuxin Gu, Yingyan Xie, Naijie Wei, Ziyang Fang, Xiaowen Yan*, Qiuquan Wang. A BTK-activatable targeted covalent NIR fluorescent probe for kinase monitoring and B-cell lymphoma imaging. Biosensors and Bioelectronics. 2025, 289, 117867.
2. Xinyue Zhao#, Naijie Wei#, Ziyang Fang, Yingyan Xie, Xiaowen Yan*, Qiuquan Wang. A Targeted Covalently Activated Chemotherapy Strategy Synergistically Enhances Cytotoxicity of Ibrutinib and Selectivity of Doxorubicin to B-cell Lymphoma Cells. Journal of Medicinal Chemistry. 2026, 69 (3), 2387−2399.
3. Xinyue Zhao#, Lulu Ning#, Xiaoman Zhou, Zhihui Song, Jianjian Zhang*, Feng Guan, and Xiao-Feng Yang. An Activatable Near-Infrared Fluorescence Hydrogen Sulfide (H2S) Donor for Imaging H2S Release and Inhibiting Inflammation in Cells. Analytical Chemistry, 2021, 93, 4894−4901.
4. Ziyang Fang#, Xinyue Zhao#, Ruxue Hou#, Yang Zhao, Lei Wang, Li Yi, Limin Yang, Xiaowen Yan*, Qiuquan Wang. Antibody-Directed Cell Internalization of Targeted Covalent Europium Tag Enables in Situ Kinase Labeling and Inductively Coupled Plasma Mass Spectrometry (ICP-MS) Quantification. Analytical Chemistry. 2025, 97, 12125−12132.
5. Xinyue Zhao#, Yang Zhao#, Ziyang Fang#, Naijie Wei, Jianbin Chen, Qiuquan Wang, and Xiaowen Yan*. Antibody-Targeted Covalent Inhibitor Conjugate (Ab-TCI) Bridged by an Arsenic-Thiol Bond Enables “Double Insurance” Targeting of Cancer Cells and Kinase for Effective Cancer Treatment. ACS Medicinal Chemistry Letters. 2026, 17, 5, 1195–1201.
Teaching
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Undergraduate Course：Biomedical Engineering Undergraduate Laboratory
